Orodental Delivery Systems: an Overview

Oral cavity can be used for local drug delivery as in for periodontitis, dental caries or for oral mucosal drug delivery as for alveolar osteitis, analgesia or transmucosal systemic effect as for smoking cessation or delivery of biotechnological products like proteins and peptides. This article gives an overview of basic structure, function, biochemistry, and permeability of the oral cavity. Different diseases affecting orodental region along with conventional as well as new and emerging drug delivery and technologies that address the unmet patient and market needs for improved local drug therapy to this region are discussed in this article. Regulatory and Clinical aspects of this type of drug delivery are very important and are taken into consideration in this article. The aim of this review is to provide the reader a general and inspiring prospect on recent and promising fields of innovation in oral drug delivery.